Simple and Rapid Synthesis of Magnetite/Hydroxyapatite Composites for Hyperthermia Treatments via a Mechanochemical Route
نویسندگان
چکیده
This paper presents a simple method for the rapid synthesis of magnetite/hydroxyapatite composite particles. In this method, superparamagnetic magnetite nanoparticles are first synthesized by coprecipitation using ferrous chloride and ferric chloride. Immediately following the synthesis, carbonate-substituted (B-type) hydroxyapatite particles are mechanochemically synthesized by wet milling dicalcium phosphate dihydrate and calcium carbonate in a dispersed suspension of magnetite nanoparticles, during which the magnetite nanoparticles are incorporated into the hydroxyapatite matrix. We observed that the resultant magnetite/hydroxyapatite composites possessed a homogeneous dispersion of magnetite nanoparticles, characterized by an absence of large aggregates. When this material was subjected to an alternating magnetic field, the heat generated increased with increasing magnetite concentration. For a magnetite concentration of 30 mass%, a temperature increase greater than 20 K was achieved in less than 50 s. These results suggest that our composites exhibit good hyperthermia properties and are promising candidates for hyperthermia treatments.
منابع مشابه
The Effect of Rotation Speed and Time of Milling on Synthesis and Properties of Fluoridated Hydroxyapatite Biomaterial
Synthetic hydroxyapatite (HA) is the most helpful because of its similarity to natural bone in both crystalline structure and chemical composition. Recently, fluoridated hydroxyapatite (FHA) has been developed in dental and orthopedic application because it has lower solubility than pure HA, while maintaining the comparable bioactivity and biocompatibility. The aim of this study was to...
متن کاملA rapid microwave route for the synthesis of ZnS nanoparticles
ZnS nanoparticles were synthesized via a simple surfactant free microwave route. In this synthesis, thioacetamide was used as sulfur source. The effects of different parameters such as type of zinc precursor, time and power of irradiation on the morphology and particle size of the products have been investigated. The nanostructures were characterized by ...
متن کاملEffect of Ultrasonic on Crystallinity of Nano-Hydroxyapatite via Wet Chemical Method
In a hydrothermal route devoted for synthesis of Ca10(PO4)6(OH)2 (HA) nanostructures, morphology can be controlled by experimental condition to form magical HA or nanostructured nanoparticles. In an intermediate condition, a novel nanostructure namely rose-like bundle of HA rod-likes was found, which is different from known HA nanostructures. The...
متن کاملFe2+ Supported on Hydroxyapatite-core-shell-γ-Fe2O3 Nanoparticles as an Inexpensive and Magnetically-recoverable Catalyst for Rapid Synthesis of Benzimidazoles and Benzoxazole Derivatives
A simple and facile method for the preparation ofFe2+ supported on hydroxyapatite-core-shell-γ-Fe2O3 nanoparticles (γ-Fe2O3@HAp-Fe2+ NPs) as an environmentally friendly and recyclable green catalyst is described and used for the one-pot synthesis of benzimidazoles and benzoxazole derivatives via reactions between aromatic aldehyd...
متن کامل